Highlights:

Skills:Drug Discovery, Medicinal Chemistry

Associate Director 11/2015 - 11/2016
LALS, HYDERABAD, TELANGANA India
Industry: PHARMACEUTICAL/BIOTECH
Inventor of APL-581 (WO/2018/098561; dual inhibitor; epigenetic & kinase) for the oncology project that showed excellent overall profile. This molecule (APL-581) has been acquired by Ohm Oncology ($125M) http://ir.aptose.com/phoenix.zhtml?c=116148&p=RssLanding&cat=news&id=2336709 https://www.fiercebiotech.com/biotech/aptose-signs-125m-plus-bet-inhibitor-deal-ohm-oncology
1. Medicinal Chemist and project leader with 10 years of experience in medicinal chemistry, drug discovery (hit identification to pre-clinical candidate), multi-step organic synthesis, team-project management, drafting, filing and updating of IPs 2. Have great expertise in oncology, endocrine diseases, neuropathic pain. Successfully led teams in highly collaborative programs and multidisciplinary projects with strong team building skills 3. My area of professional expertise relates to synthetic routes for target molecules involving heterocyclic, SAR modification (SBDD & CADD) to modulate the physicochemical and biochemical properties 4. Excellent understanding of Chemistry-Biology interface, target protein molecules, ligand-protein binding, inhibition/activation, selectivity, and various aspects of structure based drug-design 5. Have successfully applied medicinal chemistry to address ADME, PK/PD and toxicity problems. Accomplished in synthetic and medicinal chemistry with a strong track record of publications in peer-reviewed journals with several research publications and patents accredits to my competence and achievement--

Panjab University 08/1996 - 07/2000
CHANDIGARH, , India
Degree: Doctoral Degree
Major:Chemistry
Worked on the asymmetric synthesis of beta-lactam antibiotics

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