Highlights:My expertise is in multi-step organic synthesis, antibody drug conjugation, manual and automated radiolabeling, analytical techniques, in vitro binding assays, Pharmacokinetic, Biodistribution studies and small animal PET imaging. My competences include project design and management, data analysis and interpretation, development and implementation of synthetic and analytical strategies. Technical skills: • Radiochemistry: Radiolabeling small molecules with 18F and 11C and antibodies with 89Zr, 99mTc, 111In. Perform radioligand binding assays. • PET/CT imaging: operation of Micro PET/CT scanner and images reconstruction. • Analytical techniques: HPLC , SEC, LC-MS, TLC, MS, NMR, IR, SDS-Page, WB, ELISA, FACS • GMP: production of radiolabelled molecules for human use. • Medicinal Chemistry : Design and synthesis of small molecules and antibody conjugates • Cell culture: mammalian cell culture, immune cell culture. Mouse and human tumor cell culture. • Small animal experiments: Tumor cell line/drug injection to mice via IP and subcutaneously. Tumor measurement via caliper. Blood collection, organ harvesting and biodistribution assays.

Skills:Radiochemistry, PET Imaging, organic chemistry, Biochemistry, ADC, HPLC, radioligand binding assays, cell culture, Image analysis, small animals, biodistribution, small molecules, drug design, WB, ELISA, Computational chemistry

Goal:I am a passionate and self-motivated research scientist with 7 years of comprehensive experience conducting research and development programs in cancer preclinical drug development and imaging. My objective is to further my career as a preclinical scientist and lead to increasingly responsible roles in the translation of novel pharmaceuticals and imaging agents to clinic.

Postdoctoral Research Associate 02/2018 - current
Yale University, New Haven, Connecticut United States
Developed 89Zr, 99mTc, 111In radiolabelled antibodies and antibody fragments as companion diagnostic imaging agents for PET/SPECT imaging of cancer preclinical models.
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University of Rome La Sapienza 09/2007 - 11/2013
Rome, Lazio, Italy
Degree: Master's Degree
Major:Medicinal Chemistry
Minor:Pharmacology
5 years degree in Pharmaceutical chemistry and technology.

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